ChemBioPort: an online portal to navigate the structure, function and chemical inhibition of the human proteome. Read more about ChemBioPort: an online portal to navigate the structure, function and chemical inhibition of the human proteome.
Identification of Novel 2,4,5-Trisubstituted Pyrimidines as Potent Dual Inhibitors of Plasmodial PfGSK3/PfPK6 with Activity against Blood Stage Parasites In Vitro. Read more about Identification of Novel 2,4,5-Trisubstituted Pyrimidines as Potent Dual Inhibitors of Plasmodial PfGSK3/PfPK6 with Activity against Blood Stage Parasites In Vitro.
Covalent Modification of Bromodomain Proteins by Peptides Containing a DNA Damage-Induced, Histone Post-Translational Modification. Read more about Covalent Modification of Bromodomain Proteins by Peptides Containing a DNA Damage-Induced, Histone Post-Translational Modification.
Dissecting the stability determinants of a challenging de novo protein fold using massively parallel design and experimentation. Read more about Dissecting the stability determinants of a challenging de novo protein fold using massively parallel design and experimentation.
De novo design of immunoglobulin-like domains. Read more about De novo design of immunoglobulin-like domains.
A Screening of Epigenetic Therapeutic Targets for Non-Small Cell Lung Cancer Reveals PADI4 and KDM6B as Promising Candidates. Read more about A Screening of Epigenetic Therapeutic Targets for Non-Small Cell Lung Cancer Reveals PADI4 and KDM6B as Promising Candidates.
PBRM1, SETD2 and BAP1 - the trinity of 3p in clear cell renal cell carcinoma. Read more about PBRM1, SETD2 and BAP1 - the trinity of 3p in clear cell renal cell carcinoma.
The Chemical Probes Portal: an expert review-based public resource to empower chemical probe assessment, selection and use. Read more about The Chemical Probes Portal: an expert review-based public resource to empower chemical probe assessment, selection and use.
Discovery of Hit Compounds for Methyl-lysine Reader Proteins from a Target Class DNA-Encoded Library. Read more about Discovery of Hit Compounds for Methyl-lysine Reader Proteins from a Target Class DNA-Encoded Library.
Phosphorylation of the DNA repair scaffold SLX4 drives folding of the SAP domain and activation of the MUS81-EME1 endonuclease. Read more about Phosphorylation of the DNA repair scaffold SLX4 drives folding of the SAP domain and activation of the MUS81-EME1 endonuclease.