Chemical Probes

Chemical Probes

Potent, selective and cell-permeable inhibitors of protein function ("chemical probes") are valued reagents in both fundamental and applied biological research, and they are essential for the early stages of drug discovery by allowing preclinical target validation in both academic and industrial laboratories.

Donated probe website KCGS website

SGC chemical probes are open-access reagents that are meant to be used by  the biomedical research community with no restrictions on use. To acquire a sample, follow the links on the webpage of your desired chemical probe. You can sort the table by clicking the column headers.

The SGC probes set is complemented by the donated probe set

Name Structures Protein family Specific Targets Control In Vivo Activity*sort descending Added
TH-257
 		Kinase LIMK1, LIMK2 TH-263 07/17
UNC6934
 		Methyl Lysine Binder NSD2-PWWP1 UNC7145 06/19
LLY-283
 		Methyltransferase PRMT5 LLY-284 07/16
MRK-740
 		Methyltransferase PRDM9 MRK-740-NC 06/18
PFI-5
 		Methyltransferase SMYD2 PFI-5N 07/17
SGC-GAK-1
 		Kinase GAK SGC-GAK-1N 02/18
GSK4027
 		Bromodomains KAT2A, KAT2B GSK4028 06/17
T-26c
 		Protease MMP13 T-26f 06/16
BI01383298
 		Solute carriers SLC13A5 BI01372674 01/18
BAY-850
 		Bromodomains ATAD2 BAY-460 01/17
VinSpinIn
 		Spindlin domains Spin1 VinSpinIC 09/18
SGC6870
 		Methyltransferase PRMT6 SGC6870N 06/19
BI-9321
 		Methyl Lysine Binder NSD3 BI-9466 07/18
SKI-73
 		Methyltransferase CARM1 SKI-73N 07/17
A-395
 		WD40 repeat EED A-395N 07/16
SGC3027
 		Methyltransferase PRMT7 SGC3027N 03/18
BAY-6035
 		Methyltransferase SMYD3 BAY-444 06/17
SGC-STK17B-1
 		Kinase STK17B, DRAK2 SGC-STK17B-1N 02/20
TP-064
 		Methyltransferase CARM1 TP-064N 06/16
SGC-AAK1-1
 		Kinase AAK1, BMP2K, BIKE SGC-AAK1-1N 02/18
FM-381
 		Kinase JAK3 FM-479 02/17
TP-238
 		Bromodomains CECR2, BPTF TP-422 09/18
A-485
 		Lysine acetyltransferase CREBBP, EP300 A-486 10/17
SGC-SMARCA-BRDVIII
 		Bromodomains PB1(5), SMARCA2/4 SGC-BRDVIII-NC 12/20
GSK8814
 		Bromodomains ATAD2, ATAD2B GSK8815 01/17
UNC0638
 		Methyltransferase EHMT2/G9a, EHMT1/GLP UNC0737 No 06/10
PFI-6
 		YEATS MLLT1, MLLT3 PFI-6N No 06/20
NI-57
 		Bromodomains BRPF1, BRD1, BRPF3 No 12/14
GSK343
 		Methyltransferase EZH2 No 08/12
SGC-UBD253
 		HDAC6 SGC-UBD253N No 01/22
SGC0946
 		Methyltransferase DOT1L SGC0649 No 08/12
GSK591
 		Methyltransferase PRMT5 SGC2096 No 07/15
T3-CLK Kinase CLK1, CLK2, CLK3, CLK4 T3-CLK-N No 04/19
T3-CLK
 		Kinase CLK1, CLK2, CLK3, CLK4 T3-CLK-N No 05/19
NVS-MLLT-1
 		YEATS MLLT1, MLLT3 NVS-iMLLT-C No 03/20
FS-694 Kinase MAPK14 FM-743 No 01/20
IOX2
(requires >>> 1 microM for cell assays)
 		2OG PHD2 No 02/12
GSK789 Bromodomains BRD2, BRD3, BRD4, BRDT GSK791 No 02/21
PFI-1
 		Bromodomains BRD2, BRD3, BRD4, BRDT No 11/11
PFI-7
 		E3 ligase GID4 PFI-7N No 09/21
PFI-3
 		Bromodomains SMARCA2, PBRM1, SMARCA4 PFI-3oMet No 11/13
NVS-BPTF-1
 		Bromodomains BPTF NVS-BPTF-C No 02/19
SGC-CLK-1
 		Kinase CLK1, CLK2, CLK4 SGC-CLK-1N No 02/20
SR-318 Kinase MAPK14 SR-321 No 01/20
BI 99179 Synthase FASN BI 99990 No 05/18
OF-1
 		Bromodomains BRPF1, BRD1, BRPF3 No 07/14
Homer
 		WD40 repeat WDR5 nc_WDR5 and nc_VHL No 07/21
OICR-9429
 		WD40 repeat WDR5 OICR-0547 No 05/14
BI-1942 Protease CMA1 No 06/21
IOX1
(tool compound)
 		2OG Pan-KDM No 01/12
UNC1215
 		Methyl Lysine Binder L3MBTL3 UNC1079 No 08/12
NVS-PAK1-1
 		Kinase PAK1 NVS-PAK1-C No 06/16
BAY-885 Kinase MAPK7 BAY-693 No 11/18
TP-008 Kinase ACVR1B, TGFBR1 Al11 No 06/19
NR162
 		Kinase CASK NR187 No 09/20
SR-302 Kinase DDR1, DDR2, MAPK11, MAPK14 SR-301 No 06/20
LP99
 		Bromodomains BRD9, BRD7 2S,3R-enantiomer No 12/14
IPP/CNRS-A017 Dehydrogenase DHODH IPP/CNRS-A019 No 10/19
I-CBP112
 		Bromodomains CREBBP, EP300 No 03/13
MSC2711186
 		Kinase SRPK1, SRPK2, SRPK3 MSC2705360 No 02/22
SGC707
 		Methyltransferase PRMT3 XY1 No 06/14
MU1210
 		Kinase CLK1, CLK2, CLK4, DYRK1A, DYRK1B, DYRK2 MU140 No 05/19
SGC-CK2-1
 		Kinase CSNK2A1, CSNK2A2 SGC-CK2-1N No 06/20
BAY-3827 Kinase PRKAA1, RPS6KA1 BAY-974 No 01/20
GSK-J1
use pro-drug GSK-J4 for cell assays
 		Lysine Demethylase KDM6B/JMJD3, KDM6A/UTX, KDM5B/JARID1B GSK-J2 (GSK-J5) No 07/12
I-BRD9
 		Bromodomains BRD9 No 05/15
BTZO-1 Cytokine MIF BTZO-4 No 05/18
A-1596586 Ion channel CFTR A-1596584 No 06/19
Bromosporine (BSP)
(tool compound)
 		Bromodomains pan-Bromodomain No 01/13
CK156
 		Kinase STK17A, DRAK1 CKJB71 No 10/21
SGC-CBP30
 		Bromodomains CREBBP, EP300 BDOIA513 No 03/13
MS023
 		Methyltransferase PRMT1, PRMT3, CARM1, PRMT6, PRMT8 MS094 No 07/15
BAY-293 Nucleotide exchange factor SOS1 BAY-294 No 04/19
TP-008
 		Kinase ALK4, ALK5 AI11 No 05/19
PFI-4
 		Bromodomains BRPF1 No 12/14
NVS-CECR2-1
 		Bromodomains CECR2 NVS-CECR2-C No 06/15
GSK-LSD1
 		Lysine Demethylase KDM1A/LSD1 No 03/14
(R)-ZINC-3573 GPCR MRGPRX2 (S)-ZINC-3573 No 06/20
PFI-2
 		Methyltransferase SETD7 (S)-PFI-2 No 05/13
MS049
 		Methyltransferase CARM1, PRMT6 MS049N No 06/15
A-366
 		Methyltransferase EHMT1/GLP, EHMT2/G9a No 06/13
BAY-091 Kinase PIP4K2A BAY-0361 No 10/21
BAY-299
 		Bromodomains TAF1, BRD1 BAY-364 No 06/16
SGC-CAMKK2-1
 		Kinase CAMKK1, CAMKK2 SGC-CAMKK2-1N No 01/20
LLY-507
(Multiple Off-target Effects)
 		Methyltransferase SMYD2 SGC705 No 11/13
A-196
 		Methyltransferase SUV420H1, SUV420H2 A-197, SGC2043 No 07/15
UNC0642
 		Methyltransferase EHMT2/G9a, EHMT1/GLP Yes 08/12
M4K2234
 		Kinase ALK1, ALK2 M4K2234NC Yes 02/22
BI-2540 Reverse transcriptase HIV NNRT BI-2439 Yes 11/20
PF-05105679 Ion channel TRPM8 PF-05257137 Yes 05/18
PFI-653 Hydrolase VNN1 PFI-653-N Yes 09/21
GSK864
 		Dehydrogenase IDH1 GSK990 Yes 11/15
BI-4394 Protease MMP13 BI-4395 Yes 11/18
MLi-2 Kinase LRRK2 MLi-2-NC Yes 05/19
NVS-MALT1 Protease MALT1 NVS-MALT1-C Yes 02/20
GSK2801
 		Bromodomains BAZ2A, BAZ2B GSK8573 Yes 12/14
BI 665915 Lipoxygenase ALOX5AP BI-0153 Yes 05/18
GSK620 Bromodomains BRD2, BRD3, BRD4, BRDT Yes 02/21
ABT-100 Transferase FNTB A-108 Yes 05/18
TP-050 Ion channel GRIN2A TP-050n Yes 09/22
BAY-784 GPCR GNRHR BAY-786 Yes 11/18
MSD-M1PAM GPCR CHRM1 MSD-M1PAM-NC Yes 08/19
BAY-069 Amino acid transaminase BCAT1, BCAT2 BAY-771 Yes 09/20
BI-1935 Hydrolase EPHX2 BI-2049 Yes 05/18
JNJ-42396302 Phosphodiesterase PDE10A JNJ-40573663 Yes 09/21
BAY-678 Protease ELANE BAY-677 Yes 05/18
JNJ-9350 Oxidase SMOX JNJ-4545 Yes 09/22
ERKi Kinase MAPK3, MAPK1 ERKi-NC Yes 05/18
BI-9564
 		Bromodomains BRD9, BRD7 Yes 04/15
BAY-386 GPCR F2R BAY-448 Yes 05/18
BAY1125976 Kinase AKT1/2 BAY-940 Yes 11/21
TP-472
 		Bromodomains BRD9, BRD7 TP-472N Yes 06/16
BI-1950 Integrin ITGAL BI-9446 Yes 11/18
MSD-CYP11B2 Cytochrome P450 CYP11B2 MSD-CYP11B2 Negative control Yes 06/19
TP-030-1 Kinase RIPK1 TP-030n Yes 09/20
MRK-560 Protease Gamma secretase complex GSI-NC Yes 05/18
8RK64 Regulator protein UCHL1 JYQ88 Yes 09/21
GSK484
 		Arginine deiminases PAD4 GSK106 Yes 03/15
T-26c Protease MMP13 T-26f Yes 05/18
CCT369260 Transcription factor BCL6 CCT393732 Yes 09/22
A-192621 GPCR EDNRB A-1806262 Yes 03/19
BAZ2-ICR
 		Bromodomains BAZ2A, BAZ2B Yes 05/14
BAY-3153 GPCR CCR1 BAY-173 Yes 02/21
A-485 Transferase EP300, CREBBP A-486 Yes 05/18
Borussertib Kinase AKT1, AKT2 RL2578 Yes 10/21
BI 639667 GPCR CCR1 BI-9307 Yes 11/18
PPTN GPCR P2RY14 PPTN-NC Yes 06/19
Ogerin GPCR GPR68 ZINC32547799 Yes 06/20
MRL-650 GPCR CNR1 MRL-CB1-NC Yes 05/18
BAY-598
 		Methyltransferase SMYD2 BAY-369 Yes 04/15
PF-04457845 Hydrolase FAAH PF-04875474 Yes 05/18
JNJ-6204 Kinase CSNK1D/CSNK1E JNJ-0293 Yes 09/22
TP-024 GPCR GPR52 TP-024n Yes 11/18
A-1155463 Regulator protein BCL2L1 A-1107969 Yes 11/19
BAY-899 GPCR LHCGR BAY-897 Yes 01/20
MU1700
 		Kinase ALK1, ALK2 MU1700NC Yes 02/22
BI 207127 RNA polymerase HCV NS5B BI-7656 Yes 11/20
TP-004 Protease METAP2 TPn-004 Yes 05/18
MSC-4381 Monocarboxylate transporter SLC16A3 MSC-0516 Yes 09/21
L-Moses
 		Bromodomains KAT2A, KAT2B D-Moses Yes 10/17
JQ1
 		Bromodomains BRD2, BRD3, BRD4, BRDT (-)-JQ1 Yes 06/10
BAY-826 Kinase TIE1, TEK, DDR1, DDR2 BAY-309 Yes 05/18
GSK973 Bromodomains BRD2, BRD3, BRD4, BRDT GSK943 Yes 02/21
(R)-9s GPCR ADRA1D (S)-9s Yes 05/18
TP-051 GPCR FFAR1 TP-051n Yes 09/22
GSK6853
 		Bromodomains BRPF1 GSK9311 Yes 01/17
TP-020 Transferase MGAT2 TP-020n Yes 11/18
BAY-390 Ion channel TRPA1 BAY-9897 Yes 09/20
PF-04418948 GPCR PTGER2 PF-04475866 Yes 05/18
JNJ-54119936 Nuclear hormone receptor RORC JNJ-53721590 Yes 09/21
BAY-678
 		Protease ELANE BAY-677 Yes 10/15
A-079 Ion channel TRPA1 A-226 Yes 11/18
UCSF924 GPCR DRD4 UCSF924NC Yes 04/19
ABT-724 GPCR DRD4 A-769 Yes 05/18
GSK046 Bromodomains BRD2, BRD3, BRD4, BRDT Yes 02/21
GNE-2256 Kinase IRAK4 GNE-6689 Yes 11/21
BAY-1797 Ion channel P2X4 BAY-207 Yes 11/18
TP-030-2 Kinase RIPK1 TP-030n Yes 09/20
GSM1 Protease Gamma secretase complex GSM-NC Yes 05/18
TP-040 Hydrolase OGA TP-040n Yes 09/21
BAY-876 Solute carriers SLC2A1 BAY-588 Yes 05/18
SAFit2 Isomerase FKBP5 ddSAFit2 Yes 09/22
Skepinone-L Kinase MAPK14 FM-743 Yes 01/20
BAY-7598 Protease MMP12 BAY-694 Yes 05/18
GSK778 Bromodomains BRD2, BRD3, BRD4, BRDT Yes 02/21
BAY-707 Hydrolase NUDT1 BAY-604 Yes 05/18
JNJ-65355394 Hydrolase OGA JNJ-73924149 Yes 11/21
BI 653048 Nuclear hormone receptor NR3C1 BI-3047 Yes 11/18
THPP-1 Phosphodiesterase PDE10A THPP-1-NC Yes 06/19
MRIA9
 		Kinase SIK1, SIK2, SIK3 MR7 Yes 08/21
MRL-SYKi Kinase SYK MRL-SYKi-NC Yes 05/18
A-446 Hydrolase GLS A-426 Yes 07/21
ABT-546 GPCR EDNRA A-545 Yes 05/18
JNJ-39758979 GPCR HRH4 JNJ-39668551 Yes 09/22
BI-1230 Protease HCV NS3 BI-1675 Yes 03/19
BAY-985 Kinase TBK1, IKBKE BAY-440 Yes 01/20
BAY-179 Complex I BAY-070 Yes 01/20
BAY-474 Kinase MET BAY-827 Yes 05/18
BAY-6672 GPCR PTGFR BAY-403 Yes 11/20
UNC1999
 		Methyltransferase EZH2 UNC2400 Yes 05/13
BI-9627 Solute carriers SLC9A1 BI-0054 Yes 05/18
BI-2545 Phosphodiesterase ENPP2 BI-3017 Yes 11/18
BAY-549 Kinase ROCK1, ROCK2 BAY-4900 Yes 06/19
WM-1119 Transferase KAT6A, KAT6B WM-2474 Yes 06/20
CRTH2 antagonist GPCR PTGDR2 CRTH2 negative control Yes 05/18
BI 605906 Kinase IKBKB BI-5026 Yes 06/21
KISS1-305 GPCR KISS1R KISS1-543 Yes 05/18
BI-2081 GPCR FFAR1 BI-0340 Yes 09/22
TP-021 Transcription factor BCL6 TP-021n Yes 11/18
DDR-TRK-1
 		Kinase DDR, TRK DDR-TRK-1N Yes 08/18
A-1211212 Regulator protein BCL2 A-1210227 Yes 11/19
* Data includes at least one of PK, clearance, etc.

Chemical Handles


This versatile modality can be used to develop tools for proximity-inducing chemistry, tracers for target engagement assays, PROTACs, chemical inducers of degradation, and pull-down reagents. Handles bind their target with Kd < 1 micromolar. Their selectivity and cell activity has not been determined.

Chemical Handle Chemical Probe Structures Protein family Specific Targets Control In Vivo Activity*sort descending Added
PFI-E3H1 PFI-7
 		E3 ligase GID4 PFI-7N No 09/21

Please select a protein family

( ( ( ASH1L:0.42656, ( SP100:0.36789, ( SP110:0.33224, ( SP140:0.13671, SP140L:0.10984) :0.20058) :0.03793) :0.06052) :0.01373, ( ( ( ATAD2:0.26940, ATAD2B:0.26369) :0.19033, ( ( ( ( ( BRD1:0.22380, BRPF3:0.22705) :0.01451, BRPF1:0.23801) :0.20719, ( ( ( ( ( ( BRD2:0.19557, BRD3:0.19148) :0.04050, BRD4:0.25182) :0.02415, BRDT:0.28925) :0.14057, PBRM1:0.44189) :0.00803, ( CREBBP:0.20246, EP300:0.20268) :0.23148) :0.00872, ( ( BRD7:0.33523, BRD9:0.32809) :0.08483, ( CECR2:0.43144, KIAA2026:0.43985) :0.00515) :0.00941) :0.00414) :0.00503, ( ( BRWD1:0.23336, ( BRWD3:0.23371, PHIP:0.22856) :0.00717) :0.20977, ( ZMYND11:0.36547, ZMYND8:0.37118) :0.07274) :0.01167) :0.00465, ( TAF1:0.04053, TAF1L:0.04161) :0.41155) :0.00158) :0.00393, BRD8:0.44351) :0.00285) :0.00187, ( ( ( BAZ1A:0.40491, BAZ1B:0.40021) :0.02117, ( BAZ2A:0.35523, BAZ2B:0.35501) :0.06222) :0.02521, ( MLL:0.41568, ( ( ( TRIM24:0.25638, TRIM33:0.25600) :0.09230, TRIM28:0.34971) :0.03714, TRIM66:0.38654) :0.04652) :0.01663) :0.00258, ( ( BPTF:0.42133, ( KAT2A:0.15500, KAT2B:0.14788) :0.26722) :0.02034, ( SMARCA2:0.11640, SMARCA4:0.11442) :0.33318) :0.00435);
( ( ( ( JARID2:0.43039, ( ( ( ( KDM4A/JMJD2A:0.23155, KDM4C/JMJD2C:0.23341) :0.01707, KDM4B/JMJD2B:0.24566) :0.01607, ( KDM4D/JMJD2D:0.16619, KDM4DL/JMJD2E:0.17175) :0.06332) :0.15741, ( ( KDM5A/JARID1A:0.23147, KDM5B/JARID1B:0.24003) :0.02678, ( KDM5C/JARID1C:0.06805, KDM5D/JARID1D:0.07750) :0.18760) :0.14048) :0.03729) :0.01341, ( MINA:0.35985, NO66/FLJ21802:0.34553) :0.09246) :0.00726, ( ( ( JHDM1D/KIAA1718:0.30283, ( PHF2:0.26273, PHF8:0.26463) :0.04507) :0.10219, ( KDM2A/FBXL11:0.24364, KDM2B/FBXL10:0.23571) :0.16985) :0.01908, JMJD6:0.41429) :0.03462) :0.00458, ( ( JMJD1C:0.30946, ( KDM3A/JMJD1A:0.26975, KDM3B/JMJD1B:0.25258) :0.06381) :0.12378, ( JMJD5:0.43831, ( ( KDM6A/UTX:0.06705, UTY:0.06732) :0.27041, KDM6B/JMJD3:0.33895) :0.11043) :0.01232) :0.00148, ( KDM1A/LSD1:0.38589, KDM1B/LSD2:0.38297) :0.08988);
( ( L3MBTL:0.26880, ( ( L3MBTL2:0.22568, MBTD1:0.22655) :0.17920, ( ( SCMH1:0.26354, SCML2:0.26828) :0.12779, ( SFMBT1:0.22793, SFMBT2:0.23512) :0.13803) :0.02634) :0.10947) :0.01818, L3MBTL3:0.27089, L3MBTL4:0.23794);
( ( ( ( ( ( ( ASH1L:0.41664, ( ( SETD3:0.41040, SETD4:0.41233) :0.00239, SETD6:0.41336) :0.04317) :0.00783, ( ( ( ( SMYD1:0.34933, SMYD3:0.34226) :0.00652, SMYD2:0.34805) :0.05781, SMYD4:0.40382) :0.01255, SMYD5:0.42036) :0.03407) :0.00364, ( ( ( ( CARM1:0.35324, ( PRMT2:0.33715, PRMT6:0.32951) :0.01450) :0.01142, ( ( PRMT1:0.11741, PRMT8:0.11805) :0.16780, PRMT3:0.29132) :0.07270) :0.06188, ( PRMT7:0.41262, PRMT9:0.40675) :0.01709) :0.03029, PRMT5:0.44807) :0.01398) :0.00463, ( ( ( ( CAMKMT:0.42587, EEF2KMT:0.42552) :0.00950, ( ( METTL21A:0.35150, METTL21D:0.34116) :0.03059, METTL21C:0.37356) :0.05156) :0.00986, SETD2:0.41629) :0.01686, ( ( ( ( ( ( EHMT1/GLP:0.26312, EHMT2/G9A:0.26663) :0.10422, ( SUV39H1:0.20671, SUV39H2:0.20548) :0.16629) :0.02669, ( SETDB1:0.34392, SETDB2:0.35705) :0.06209) :0.01897, SETMAR:0.43380) :0.00575, ( NSD1:0.28947, ( WHSC1:0.28335, WHSC1L1:0.28588) :0.02046) :0.12647) :0.01053, ( ( ( EZH1:0.17720, EZH2:0.17535) :0.24657, SETD7:0.43372) :0.01694, ( ( MLL:0.31117, MLL4:0.31609) :0.05423, SETD8:0.39677) :0.03148) :0.00684) :0.00558) :0.00421) :0.00550, ( ( ( ( MECOM:0.23499, PRDM16:0.22172) :0.19790, ( PRDM13:0.40625, PRDM8:0.41523) :0.01377) :0.01047, ( METTL20:0.41561, PRDM2:0.40118) :0.02407) :0.00891, ( ( ( PRDM1:0.41095, ( ( ( PRDM12:0.34755, PRDM6:0.35817) :0.02348, PRDM14:0.38137) :0.01014, PRDM4:0.40304) :0.01522) :0.00630, ( ( PRDM15:0.36547, PRDM5:0.38056) :0.03066, ( PRDM7:0.13090, PRDM9:0.11910) :0.29272) :0.00897) :0.00944, ( PRDM10:0.41440, PRDM11:0.41339) :0.00558) :0.02345) :0.00880) :0.00378, ( MLL5:0.34249, SETD5:0.34753) :0.10101) :0.00319, ( DOT1L:0.43970, ( ( FBL:0.43564, ( PCMT1:0.41513, ( SETD1A:0.30089, SETD1B:0.30309) :0.09786) :0.01938) :0.00301, ( MLL2:0.34090, MLL3:0.34348) :0.05345) :0.01186) :0.00212, ( SUV420H1:0.28698, SUV420H2:0.27795) :0.16293);
( ( SPIN1:0.05966, SPIN3:0.09538) :0.01442, ( SPIN2A:0.00390, SPIN2B:0.00000) :0.15225, SPIN4:0.19320);
( ( ( ( ( ( ( ( ( ( ( ( ( A6NM71:0.19599, WDR45:0.20470) :0.09963, WDR45B:0.29608) :0.08691, ( WIPI1:0.23323, WIPI2:0.23314) :0.16096) :0.05462, ( HPS5:0.42495, ( Q6ZS54:0.07930, TECPR2:0.06531) :0.34740) :0.02830) :0.00738, ( ( ( ( ( B3KP68:0.02958, IFT172:0.01983) :0.40428, ( H3BRJ5:0.08519, IFT80:0.08212) :0.34677) :0.01950, ( ( ( ( B4DGB7:0.10634, ( FLJ00025:0.01620, IFT122:0.01417) :0.08590) :0.33152, ( B4E286:0.00099, WDR19:-0.00021) :0.43697) :0.00625, ( B4DX09:0.00715, WDR11:-0.00715) :0.43568) :0.00117, WDR35:0.44480) :0.00621) :0.00259, ( NOL10:0.43979, ( WDR4:0.40993, WDR87:0.39832) :0.01255) :0.01757) :0.00463, ( ( C2ORF44:0.45495, ( RIC1:0.42645, WDPCP:0.44085) :0.01431) :0.01021, ( ( CFAP43:0.40442, WRAP73:0.39775) :0.03042, ( ( CIRH1A:0.01057, UTP4:-0.01057) :0.26437, UTP4B:0.22739) :0.15541) :0.01526) :0.00324) :0.00174) :0.00345, ( ( ( ( ( ARPC1A:0.15819, ARPC1B:0.15532) :0.26205, TULP4:0.42618) :0.01479, ( B4DT22:0.02871, PPWD1:0.02811) :0.42170) :0.00791, ( ( 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((MLLT1:0.23658,MLLT3:0.23569):0.22518,YEATS2:0.36660,YEATS4:0.35586);
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